The Leandro De Niro Rodriguez Foundation is a heartfelt tribute to my son, a lasting expression of my love for him.

Built to honor him and shape a better future.

Let’s end the opioid crisis and empower the next generation to fight the rise of synthetic drug dangers.

Our Mission: Empowering Young Adults and Families, Together.

You Are Not Alone

The Leandro De Niro Rodriguez Foundation is dedicated to protecting every household from the devastating dangers of fentanyl. Our work is rooted in protection, prevention, and support, ensuring that families and young people have the knowledge, resources, and community they need to stay safe.


We are here to help people understand the reality of fentanyl, the risks facing young adults, and how to start open, honest conversations with their loved ones. We believe in a world where seeking help carries no stigma, no shame, only compassion.

Through education, advocacy, and community-driven programs, we strive to expand access to prevention tools, recovery support, and trauma-informed care. No one should have to face this crisis alone and with the proper support, no one has to.

Changing the Conversation. Saving Lives.

Together, we are shifting the narrative—bringing understanding where there is confusion, empowerment where there is fear, and hope where there is heartbreak. By standing with families across the country, we honor the lives already lost and protect those still at risk.

ā€œThe U.S. Drug Enforcement Administration has said, Fentanyl is the single deadliest drug threat our nation has ever encountered.ā€

ā€œIn 2023 alone, the DEA seized enough fentanyl to kill the entire U.S. population. The CDC reports that more than 74,000 Americans died from fentanyl-related overdoses in 2022 — a number that continues to rise.ā€

This crisis demands action. And we ask you to join us.

Your support fuels meaningful change, helping us build a safer future where illicit and synthetic drugs no longer steal the lives of our loved ones.

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Drena De Niro, My Story.

I created this foundation in loving memory of my son, Leandro De Niro Rodriguez. He brought so much joy and light to everyone who knew him. His presence had a magical way of lifting the energy in any room. Although his life was tragically cut short by fentanyl poisoning in July of 2023, his dreams and the spirit he shared continue to inspire us all. This story is not just about loss; it serves as a powerful reminder of the potential taken too soon by fentanyl.

Losing Leo has truly motivated me to ensure his memory leaves a positive mark on the world. I want to provide support and raise awareness for families who need it most. Through my foundation, I hope we can reduce the stigma surrounding drug use and drug-related deaths, restore dignity to the lives of victims, and offer compassionate support to their families with a growing array of resources. Together, we can ensure that no one has to face this crisis alone. This journey isn’t mine alone; it resonates with countless other families. That’s why this fight is urgent, and that’s why we won’t stop until we help save more lives.

You Can't Spell Love Without Leo

You Can't Spell Love Without Leo

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Thank You, Your Support Makes Prevention Possible

Every contribution brings us one step closer to protecting young adults, supporting families, and preventing more lives from being lost to fentanyl. This crisis is devastating, but together, we can save lives, expand awareness, and build a future where no family faces this alone.

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